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April 16, 2026Annals of Geriatric Medicine and Research0 citationsOpen Access

High-intensity statin therapy and functional independence after acute ischemic stroke in adults aged 75 years and older: a retrospective, single-center cohort study

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HCHeesun ChoiSeoul National University of Science and TechnologyELEung-Joon LeeSeoul National University HospitalMKMee Jee KimSeoul National University Hospital

Key Points

  • The aim is to investigate the effects of high-intensity statin therapy on functional independence in older adults post-acute ischemic stroke.
  • Conducted a retrospective cohort study
  • Focused on adults aged 75 years and older with acute ischemic stroke
  • Assessed functional outcomes and potential harm from statin therapy
  • High-intensity statin therapy was associated with better functional outcomes
  • No evidence of increased harm was reported
  • Findings align with current clinical guideline recommendations for treatment.

Abstract

In older patients with AIS, HIST was independently associated with better functional outcomes without evidence of increased harm, broadly consistent with current guideline recommendations for HIST when tolerated. Prospective studies are needed to confirm a causal relationship.

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Cite This Study

Choi et al. (2026) studied this question.

synapsesocial.com/papers/69e07d3c2f7e8953b7cbe446https://doi.org/10.4235/agmr.25.0202
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