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April 16, 2026Open Access

Health-related Quality of Life and Psychiatric Morbidity among Children and Adolescents with Cleft Lip and/or Palate and Their Mothers Attending the Cleft Clinic at the Armed Forces Specialist Hospital, Kano, Northwest Nigeria

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Authors

AYA YakubuRARafael A. AdebolaMBM Bardi

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Overview

Longitudinal study assesses quality of life and psychiatric morbidity in children with cleft lip and palate, suggesting need for integrated mental health services.

Key Points

  • This study aims to evaluate health-related quality of life and psychiatric morbidity among children and adolescents with cleft lip and/or palate and their mothers.
  • Longitudinal study involving 250 mother-child dyads
  • Assessment tools used included Pediatric Quality of Life Inventory and WHO Quality of Life-BREF
  • Psychiatric morbidity evaluated pre- and 6 months postsurgery
  • Data analyzed using statistical methods like McNemar’s test and logistic regression
  • High presurgical psychiatric morbidity reported among mothers (depression: 46%, anxiety: 42%) and children (depression: 20%, anxiety: 22%)
  • 60%-68% experienced poor health-related quality of life before surgery
  • Significant improvements in all HRQoL domains and reductions in psychiatric symptoms post-surgery (P < 0.001)
  • Poor maternal HRQoL independently predicted child depression (adjusted odds ratio = 2.95)

Cite This Study

Yakubu et al. (2025) studied this question.

synapsesocial.com/papers/69e07d732f7e8953b7cbe711https://doi.org/10.4103/africpcj.africpcj_13_25
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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

  1. 1Global, regional, and national burden of orofacial clefts, 1990–2021: an analysis of data from the global burden of disease study 20212025 · 8 citations