Electroreductive deconstruction and oxygenation of cyclic amines

Key Points

• To develop a greener and sustainable approach for functionalizing cyclic amines into δ-substituted amides.
• Utilized electroreductive deconstruction to cleave C-N bonds
• Achieved an E-Factor of 0.9 indicating atom economy
• Explored various transformations of cyclic amines
• Successfully transformed cyclic amines into δ-substituted amides
• Demonstrated high efficiency in bond cleavage
• Presented a sustainable alternative to traditional methods