Beyond HER2 ‐Negative: Clinical and Molecular Relevance of HER2 ‐Ultralow Expression in Gynecologic Pathology

Key Points

• Investigate the clinical and molecular implications of ultralow HER2 expression in gynecologic conditions.
• Performed analyses of HER2 expression levels in gynecologic samples.
• Examined clinical outcomes associated with HER2 ultralow expression.
• Reviewed literature on HER2's role beyond negative status.
• HER2 ultralow expression correlates with specific clinical outcomes.
• Clinical outcomes suggest a potential role for HER2 evaluation in treatment decisions.