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November 17, 2009New England Journal of Medicine3,074 citationsOpen Access

Advanced Heart Failure Treated with Continuous-Flow Left Ventricular Assist Device

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MSMark S. SlaughterJRJoseph G. RogersCMCarmelo A. Milano

Structured PICO

Does a continuous-flow left ventricular assist device improve survival free from stroke and device failure in patients with advanced heart failure compared to a pulsatile device?

P
Population
patients with advanced heart failure
I
Intervention
continuous-flow left ventricular assist device
C
Comparator
pulsatile device
O
Outcome
survival free from stroke and device failure at 2 yearscomposite

Continuous-flow LVADs provide superior 2-year survival free from stroke and device failure compared to pulsatile devices in patients with advanced heart failure.

Abstract

Treatment with a continuous-flow left ventricular assist device in patients with advanced heart failure significantly improved the probability of survival free from stroke and device failure at 2 years as compared with a pulsatile device. Both devices significantly improved the quality of life and functional capacity. (ClinicalTrials.gov number, NCT00121485.)

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Cite This Study

Slaughter et al. (2009) studied this question.

synapsesocial.com/papers/69e0c8353dcc343e9cc12048https://doi.org/10.1056/nejmoa0909938
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