Increased Primary Bile Acids with Ileocolonic Resection Impact Ileal Inflammation and Gut Microbiota in Inflammatory Bowel Disease

Elevated primary BAs were associated with ileitis, and reduced microbial diversity, F. prausnitzii abundance and enzymatic abundance of MetY acetate and l-methionine-producing enzyme expressed by F. prausnitzii, and were the only factors associated with these findings after ileocolectomy.