Experimental study demonstrates that VEGF drives miR-17-92 cluster expression in endothelial cells via ERK/ELK1, indicating a regulatory mechanism in angiogenesis.
Taken together, our results indicate that VEGF-induced miR-17-92 cluster expression contributes to the angiogenic switch of ECs and participates in the regulation of angiogenesis.
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Chamorro-Jorganes et al. (2015) studied this question.
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