Mechanical thrombectomy significantly reduced systolic pulmonary artery pressure by a mean of 13.6 mmHg and pulmonary capillary wedge pressure by 4.0 mmHg in patients with intermediate-high-risk pulmonary embolism.
Observational (n=26)
No
Does mechanical thrombectomy improve left ventricular filling in patients with intermediate-high-risk pulmonary embolism?
Mechanical thrombectomy in intermediate-high-risk PE provides a mechanistic benefit by relieving RV overload and enhancing LV filling, which may improve systemic perfusion.
Absolute Event Rate: 46.2% vs 64.4%
p-value: p=<0.0001
Mechanical thrombectomy in intermediate-high-risk PE not only relieves RV overload but also enhances LV filling by mitigating ventricular interdependence. These findings provide a mechanistic explanation for improved systemic perfusion and warrant confirmation in prospective studies.
Alban et al. (Wed,) conducted a observational in Intermediate-high-risk pulmonary embolism (n=26). Mechanical thrombectomy (FlowTriever system) vs. Baseline (pre-intervention) was evaluated on Systolic pulmonary artery pressure (sPAP) (p=<0.0001). Mechanical thrombectomy significantly reduced systolic pulmonary artery pressure by a mean of 13.6 mmHg and pulmonary capillary wedge pressure by 4.0 mmHg in patients with intermediate-high-risk pulmonary embolism.