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Research shows optimized outcomes for pleural mesothelioma through biomarker-driven therapies and AI in high-risk groups, implying advanced care strategies.
These developments underline a move away from aggressive surgical cytoreduction towards more biologically-informed, less invasive management and earlier detection in high-risk cohorts, while embracing biomarker-driven systemic and intrapleural therapies to optimize outcomes. Future research should prioritize mesothelioma-specific trials to define the role and sequencing of perioperative immunotherapy and novel agents. AI tools may assist disease diagnosis, prognostication, and treatment selection.
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Tan et al. (2026) studied this question.
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