Impact of Mild Autonomous Cortisol Secretion on Bone Density, Metabolism, and Microstructure: A Cross-sectional Study

Key Points

• This research aims to explore the effects of mild autonomous cortisol secretion on bone density and microstructure.
• Cross-sectional design assessing osteoporosis-related variables.
• Evaluated patients with mild autonomous cortisol secretion.
• Used DXA scanning to measure bone density.
• Analyzed microstructural integrity through additional assessments.
• Notable microstructural deterioration observed in patients.
• Routine DXA aBMD testing failed to detect these changes.
• Link established between cortisol levels and bone health.