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April 18, 2026Journal of Surgical Oncology0 citations

Pelvic MRI Following Total Neoadjuvant Therapy for Rectal Cancer Poorly Predicts a Complete Clinical Response

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NSNicholas R. SussRJRyan JohnsonKOKinga S. Olortegui

Key Points

  • The study aims to evaluate the predictive value of pelvic MRI after total neoadjuvant therapy in rectal cancer.
  • Analyzed endoscopic findings in patients with rectal cancer
  • Compared results of initial positive MRIs with long-term outcomes
  • Followed up with patients over a period of 4 years
  • Two-thirds of patients with initially positive MRIs showed no regrowth after 4 years
  • Indicates a mismatch between MRI results and actual clinical outcomes
  • Suggests limited reliability of MRI for predicting complete response in this context

Abstract

Two-thirds of endoscopically negative patients with initially positive restaging MRIs showed no regrowth after 4 years.

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Cite This Study

Suss et al. (2026) studied this question.

synapsesocial.com/papers/69e3203440886becb653f53fhttps://doi.org/10.1002/jso.70263
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