A dual lock-and-key activated theranostic tool for highly specific near-infrared imaging and photodynamic/chemodynamic synergistic therapy of hepatocellular carcinoma

Key Points

• The central aim is to develop a dual-responsive agent for specific imaging and treatment of hepatocellular carcinoma (HCC).
• Developed a theranostic agent HTQ-Fc.
• Utilized near-infrared (NIR) fluorescence for imaging.
• Applied photodynamic and chemodynamic therapies simultaneously.
• Achieved specific visualization of HCC in real-time.
• Demonstrated significant tumor suppression using the therapy.