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April 18, 2026Food & Function1 citations

Fucoidan Alleviates Kidney Fibrosis by Shaping the Gut Microbiota and Modulating Tryptophan Metabolism

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YZYing ZhangJLJinxin LiWCWanting Chen

Key Points

  • The aim is to investigate how fucoidan influences kidney fibrosis through gut microbiota alteration and tryptophan metabolism.
  • Utilized animal models of chronic kidney disease
  • Administered fucoidan to measure effects on renal fibrosis
  • Analyzed changes in gut microbiota composition
  • Evaluated tryptophan metabolic pathways
  • Fucoidan significantly reduced kidney fibrosis markers
  • Altered gut microbiota profile favorably
  • Enhanced tryptophan metabolism pathways related to kidney health

Abstract

Chronic kidney disease (CKD) is a major global health burden, with renal fibrosis as the key pathological driver of disease progression. Fucoidan (FPS) is a sulfated polysaccharide from brown algae...

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Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/69e3216540886becb6540aechttps://doi.org/10.1039/d6fo00785f
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