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January 24, 2025PLoS ONEOpen Access

Expanded non-invasive prenatal testing offers better detection of fetal copy number variations but not chromosomal aneuploidies

Shaozhe Yang Yuan Zhuang Junfeng Li Xiuhong Fu

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Abstract

By enhancing sequencing data, NIPT-plus can effectively screen for CNVs as well as chromosomal aneuploidies. However, NIPT-plus does not have an advantage over standard NIPT in screening for chromosomal aneuploidies.

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Yang et al. (2025) studied this question.

synapsesocial.com/papers/69e340c9029746a715d37d16 https://doi.org/10.1371/journal.pone.0312184

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