Why the study?
What are the predictive values of lipid parameters and other variables for carotid intima-media thickness and plaque in general Chinese adults?
What are the predictive values of lipid parameters and other variables for carotid intima-media thickness and plaque in general Chinese adults?
Total cholesterol, LDL-C, and non-HDL-C are strong predictors of carotid IMT and plaque in Chinese adults, with non-HDL-C demonstrating predictive value non-inferior to LDL-C.
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May support lipid-based carotid atherosclerosis risk stratification in Chinese adults; leaves open causality and generalizability to other populations.
Age, gender, SBP are important predictors for carotid IMT. Age, gender, DBP and TC are important predictors for carotid plaque. TC, LDL-C and non-HDL-C have greater predictive values for IMT and the presence of carotid plaque compared with other lipid parameters, among which TC has the greatest predictive value for the presence of carotid plaque. The predictive value of non-HDL-C for carotid IMT and plaque is not inferior to that of LDL-C.
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Hou et al. (2018) studied this question.
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