Why the study?
Is infective endocarditis in hypertrophic cardiomyopathy associated with outflow obstruction?
Is infective endocarditis in hypertrophic cardiomyopathy associated with outflow obstruction?
Antibiotic prophylaxis for infective endocarditis in HCM may only be necessary for patients with outflow obstruction.
Endocarditis risk in HCM was associated with obstruction; hypothesis-generating for targeted prophylaxis, needs prospective confirmation.
Endocarditis in HCM is virtually confined to patients with outflow obstruction and is more common in those with both obstruction and atrial dilatation. These results indicate that antibiotic prophylaxis is required only in patients with obstructive HCM.
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Spirito et al. (1999) studied this question.
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