Impact of perioperative glucocorticoids on postoperative recurrence and complications in chronic subdural hematoma: a systematic review and meta-analysis

Perioperative glucocorticoid therapy appears to reduce postoperative recurrence of chronic subdural hematoma. No clear increase in infection was observed, while the evidence for mortality remains imprecise and cannot exclude potential harm. However, glucocorticoids were associated with a higher risk of psychiatric symptoms compared with placebo. Clinicians should balance the benefit of reduced recurrence against the increased likelihood of psychiatric adverse events when considering glucocorticoids as adjuvant therapy in patients with CSDH.