This response highlights a MATLAB toolbox that simplifies analyzing extracellular spike data, aiding researchers with limited coding skills.
Extracellular electrophysiology has been part of the neuroscientist's toolbox for many decades, allowing the study of neuronal activity with high temporal resolution.By analysing the internal correlations of neuronal activity, as well as those with environmental stimuli and with behaviour, extracellular electrophysiology has been key to significant advances across the field of neuroscience, from sensory perception to cognition.It is not surprising, therefore, that its expansion shows no signs of slowing, with new technologies allowing both the recording and the analysis of many neurons simultaneously (Steinmetz et al., 2018).Yet, careful manual curation of the recorded data remains a necessary step to obtain reliable and reproducible results, and this process, along with subsequent data processing, can represent a daunting challenge for researchers with limited coding skills.Dr. Stttgen presents "MLIB: an easy-to-use MATLAB toolbox for the analysis of extracellular spike data",
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Maik C. Stüttgen (2026) studied this question.
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