Five-Year Follow-up of a Multicenter Randomized Controlled Trial Comparing an Aragonite-Based Scaffold With Microfracture and Debridement for Chondral and Osteochondral Knee Lesions
This research aims to evaluate the long-term effectiveness of an aragonite-based scaffold compared to standard surgical options for knee lesions.
Conducted as a multicenter randomized controlled trial
Evaluated patients with chondral and osteochondral knee lesions
Followed participants for five years post-intervention
Aragonite-based scaffold demonstrated superior clinical outcomes compared to SSOC
Results confirmed safety of the scaffold
Improvements noted in patients with mild to moderate osteoarthritis over five years
Abstract
The results confirmed that the aragonite-based scaffold is both safe and superior to SSOC in improving clinical outcomes at up to 5 years' evaluation, as well as in patients with mild to moderate OA.