Lung nodule detection remains a critical challenge in clinical diagnostics due to the small size, weak contrast, and high background interference of nodules in CT scans. To address these issues, a novel deep neural network architecture, termed Daisy-Net, is proposed. This model incorporates dual attention mechanisms and inter-scale feature perception, consisting of two primary components: the Parallelized Patch and Spatial Context Aware (PPSCA) module and the Omni-domain Multistage Fusion (OMF) module. The PPSCA module enhances the extraction of fine-grained textures and boundary information through multi-branch patch perception and spatial attention. The OMF module employs omni-domain feature fusion and progressive stage-wise supervision to improve robustness and discrimination under complex conditions. The lung nodule detection task is formulated as a two-dimensional segmentation problem and evaluated on the LUNA16 dataset. In the post-binarization comparative evaluation, Daisy-Net achieves the best overall performance among all compared methods, with an Intersection over Union (IoU) of 81.41, a Dice coefficient of 89.75, a precision of 95.34, a sensitivity of 84.78, and a specificity of 99.9974. These findings indicate the model’s strong capability in detecting small pulmonary nodules accurately and reliably.
Zhu et al. (Fri,) studied this question.