Observational update finds improved staging accuracy in clinically node-negative Merkel cell carcinoma, suggesting better management strategies.
MCC demonstrates a high rate of subclinical nodal metastases, with a SLNB positivity rate of nearly 40% in our series. These findings support the use of SLNB in the management of clinically node-negative MCC to improve staging accuracy, prognostication and guide management decisions, with an acceptable false-negative rate under close surveillance.
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Ahn et al. (2026) studied this question.
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