New Insights Into Metandienone Metabolism by Untargeted Gas Chromatography–High‐Resolution Mass Spectrometry

This approach meets the analytical requirements for detecting the principal metabolites associated with metandienone administration. Its primary innovation lies in the simultaneous identification of key metabolites associated with this compound intake within a single analytical workflow, encompassing metabolites previously reported separately in the literature. Furthermore, the method demonstrates improved capability for identifying potential novel metabolic markers. Overall, its application represents an alternative analytical strategy that enables the acquisition of a more comprehensive metabolic profile while improving analytical efficiency in terms of time and resource use.