What question did this study set out to answer?

To determine if lacrimal gland ultrasound can differentiate between Sjögren’s disease and non-Sjögren’s sicca patients.

April 19, 2026Open Access

Does lacrimal gland ultrasound discriminate between Sjögren’s disease and non-Sjögren’s sicca patients?

NSNRF SluijpersUniversity Medical Center Groningen TYT YangUniversity Medical Center Groningen ASAJ StelUniversity Medical Center Groningen

Key Points

To determine if lacrimal gland ultrasound can differentiate between Sjögren’s disease and non-Sjögren’s sicca patients.
Utilized lacrimal gland ultrasound (LGUS) with color Doppler (CD) imaging for assessment.
Compared characteristics of Sjögren’s disease (SjD) and non-Sjögren’s disease (non-SjD) sicca patients.
Analyzed findings to evaluate discriminatory capabilities.
Lacrimal gland ultrasound demonstrated similar characteristics in both patient groups.
Limited discriminatory value was observed between SjD and non-SjD sicca patients.
A call for refined ultrasonographic scoring systems was indicated.

Abstract

LGUS CD demonstrated similar characteristics in SjD and non-SjD sicca patients, suggesting limited discriminatory value. Refined ultrasonographic scoring systems are needed to improve differentiation between these patient groups.

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