The Role of EMMPRIN Levels in Uterine Ligaments in Pelvic Organ Prolapse

Key Points

• To investigate the relationship between EMMPRIN levels in uterine ligaments and the occurrence of pelvic organ prolapse (POP).
• Analysis of EMMPRIN levels in uterosacral ligament, cardinal ligament, and ligamentum rotundum.
• Comparison between patients with pelvic organ prolapse and healthy subjects.
• EMMPRIN levels were significantly lower in patients with pelvic organ prolapse.
• Deficiency of EMMPRIN may contribute to the development of pelvic organ prolapse.