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Markov chain marginal bootstrap (MCMB) is a new method for constructing confidence intervals or regions for maximum likelihood estimators of certain parametric models and for a wide class of M estimators of linear regression. The MCMB method distinguishes itself from the usual bootstrap methods in two important aspects: it involves solving only one-dimensional equations for parameters of any dimension and produces a Markov chain rather than a (conditionally) independent sequence. It is designed to alleviate computational burdens often associated with bootstrap in high-dimensional problems. The validity of MCMB is established through asymptotic analyses and illustrated with empirical and simulation studies for linear regression and generalized linear models.
He et al. (Sun,) studied this question.