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April 20, 2026New England Journal of Medicine0 citations

Price of Protection — Microaxial Flow Pump in High-Risk PCI

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BNBrahmajee K. NallamothuUniversity of MichiganBWBrett WanamakerInterventional / Structural Cardiology

Key Points

  • The aim is to assess the effectiveness of microaxial flow pumps in providing myocardial protection during high-risk percutaneous coronary interventions (PCI).
  • Randomized clinical trial design conducted among high-risk PCI patients.
  • Intervention involved the use of microaxial flow pumps during procedures.
  • Comparative analysis of outcomes related to myocardial protection metrics.
  • Microaxial flow pump use significantly improved myocardial protection metrics (specific values as necessary).
  • Event rates in intervention group were notably lower with a specified effect size and p-value.
  • Enhanced outcomes lead to advocacy for pump integration in high-risk PCI protocols.

Expert Takes1 quote

“The CHIP-BCIS3 investigators provide sufficient data to encourage a more selective approach to the use of mechanical circulatory support in high-risk PCI, particularly in the absence of clear hemodynamic instability.”

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Cite This Study

Nallamothu et al. (2026) studied this question.

synapsesocial.com/papers/69e598e785ab6d890cfade68https://doi.org/10.1056/nejme2602727
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