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Population-wide cohort study identifies survival outcomes linked to antiseizure medications in dementia and epilepsy, suggesting treatment guidelines.
In this population-wide cohort study, use of valproate was associated with the highest risk of death in persons with epilepsy and dementia. Lamotrigine and, in some models, levetiracetam were associated with better survival than both valproate and carbamazepine. This provides real-world support for existing expert guidelines.
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Zelano et al. (2026) studied this question.
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