A prospective study demonstrates rapid efficacy of spesolimab in generalized pustular psoriasis, suggesting improved treatment approaches.
Spesolimab demonstrated rapid and marked efficacy with excellent tolerability in GPP flares, regardless of IL36RN mutation status. Most cases had sustained remission, yet relapse occurred in a minority of patients. This calls for further research to optimize long-term and maintenance therapy.
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Bahloul et al. (2026) studied this question.
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