Does the McMahon score improve the early and specific prediction of AKI in patients with rhabdomyolysis compared to creatine kinase?
The McMahon score is a superior, earlier predictor for AKI risk in rhabdomyolysis compared to creatine kinase, helping to identify patients who may benefit from high-volume fluid resuscitation.
Creatine kinase is not a specific or early predictor of AKI in patients with rhabdomyolysis. Although a PEAK creatine kinase of at least 5000 Ul has sensitivity acceptable for screening purposes, this is often a delayed finding. A McMahon score of at least 6 calculated on admission allows for a more sensitive, specific and timely identification of patients who may benefit from high-volume fluid resuscitation.
Simpson et al. (Thu,) studied this question.