Carcinoma en Cuirasse (CeC) and Radiation-Induced Morphea (RIM) are two discrete and rare diagnoses, most commonly found among patients treated for breast cancer.Due to their similar clinical presentation and extremely low incidence rates, it can be challenging for providers to differentiate the pathologies promptly and accurately.This report describes a woman who developed CeC while undergoing adjuvant radiation therapy (RT) to the right chest wall and regional lymph nodes for triple-negative breast cancer.It is contrasted to a case of a woman with metastatic hormone receptor positive breast cancer who developed RIM eight years after adjuvant RT to the left breast and regional lymph nodes.Both cases depended upon targeted punch biopsy for histologic diagnosis.CeC was treated with prompt initiation of next-line chemotherapy and additional RT.RIM was treated with topical corticosteroids and immunosuppressants.The comparison of these cases delineates how these pathologies can be identified and treated promptly and accurately.
Grace et al. (2026) studied this question.