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Investigating how a paternal diet rich in trans fatty acids and vitamin E affects gene expression related to lipid metabolism in offspring.

April 21, 20260 citations

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Differential expression of Pparγ target genes in testis of rats under theinfluence of paternal trans fatty acid and vitamin-E.

SVSoheil VesalUniversity of Science and Culture DKDanial Hashemi KaroiiUniversity of Tehran ASAmir Abbas ShamsUniversity of Science and Culture

Key Points

Investigating how a paternal diet rich in trans fatty acids and vitamin E affects gene expression related to lipid metabolism in offspring.
Examined differential gene expression of Pparγ targets in testis of rats.
Analyzed the impact of trans fatty acids and vitamin E on metabolic pathways.
Utilized standard genetic and biochemical techniques to assess changes.
Altered expression of Pparγ target genes was observed in the testis of offspring.
Measurable changes in lipid metabolism were linked to the paternal diet.
Impacts on reproductive health parameters were noted.

Abstract

Our findings demonstrate the metabolic impact of paternal diet on offspring's, with focus on mechanisms related to altered lipid metabolism and reproductive health.

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Differential expression of Pparγ target genes in testis of rats under theinfluence of paternal trans fatty acid and vitamin-E.

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Abstract

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