Why the study?
Do C-Reactive Protein levels predict future risk of coronary heart disease in initially healthy middle-aged men?
Do C-Reactive Protein levels predict future risk of coronary heart disease in initially healthy middle-aged men?
C-Reactive Protein serves as a sensitive systemic marker of inflammation that predicts future risk of coronary heart disease in initially healthy middle-aged men.
CRP may refine CHD risk stratification in middle-aged men; leaves open whether targeting inflammation prevents events.
These results confirm the prognostic relevance of CRP, a sensitive systemic marker of inflammation, to the risk of CHD in a large, randomly selected cohort of initially healthy middle-aged men. They suggest that low-grade inflammation is involved in pathogenesis of atherosclerosis, especially its thrombo-occlusive complications.
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Köenig et al. (1999) studied this question.
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