Why the study?
Does empagliflozin improve atrial remodeling and mitochondrial function in high-fat diet/streptozotocin-induced diabetic rats?
Population
High-fat diet/streptozotocin-induced diabetic rats
Comparison
Empagliflozin administration
Authors
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Hypothesis-generating in diabetic rats; human trials needed before considering empagliflozin for T2DM-related atrial remodeling.
Does empagliflozin improve atrial remodeling and mitochondrial function in high-fat diet/streptozotocin-induced diabetic rats?
Empagliflozin may help prevent T2DM-related atrial fibrillation by ameliorating atrial structural and electrical remodeling and improving mitochondrial function.
Shao et al. (2019) studied this question.
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