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April 22, 20260 citationsOpen Access

Computer-Assisted Surgery is Associated with Reduced Inflammatory Response in Total Knee Arthroplasty: A Randomized Double-Blinded Control Trial.

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PCPruk ChaiyakitNavamindradhiraj UniversityTTTheerasak TempaiboolkulNavamindradhiraj UniversitySHSittisak HonsawekThai Red Cross Society

Key Points

  • This research aims to evaluate the inflammatory response associated with computer-assisted total knee arthroplasty (CAS-TKA) compared to conventional techniques.
  • Conducted as a randomized double-blinded control trial.
  • Compared inflammatory markers between CAS-TKA and conventional total knee arthroplasty (CON-TKA).
  • Measured serum IL-6 and erythrocyte sedimentation rate (ESR) at 2 weeks post-surgery.
  • CAS-TKA showed a lower inflammatory response than CON-TKA.
  • sIL-6 and ESR levels had smaller changes in CAS-TKA patients.
  • Functional benefits of CAS-TKA require further investigation.

Abstract

Compared with CON-TKA, CAS-TKA had a lower inflammatory response and a smaller change in sIL-6 and ESR levels at 2 weeks after surgery. However, its functional benefits should be further investigated.

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Cite This Study

Chaiyakit et al. (2026) studied this question.

synapsesocial.com/papers/69e864866e0dea528dde9458https://doi.org/10.22038/abjs.2025.87793.3975
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Computer‐assisted revision total knee arthroplasty does not improve postoperative knee prosthesis alignment compared to the conventional technique2024 · 1 citations
  2. 2Artroplastia total de rodilla: uso de cirugía robótica versus cirugía convencional: Scoping review2026
  3. 3Short-Term Outcomes of Total Knee Arthroplasty Using a Conventional, Computer-Assisted, and Robotic Technique: A Pilot Clinical Trial2024 · 10 citations
  4. 4The Cost-Effectiveness of Computer-Assisted Compared with Conventional Total Knee Arthroplasty2024 · 6 citations
  5. 5Comparison of serum systemic inflammatory biomarkers in bone-milling robotic-assisted total knee arthroplasty and conventional total knee arthroplasty: a prospective randomized controlled trial2026