Using Light for Degradation: Photo-induced Scission of Monomers and Initiators for Biocompatible Polymers

April 1, 2026Open Access

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Key Points

The research aims to develop biocompatible polymers through innovative photopolymerisation techniques.
Explored orthogonal photospaltbare hydrogels using UV-light and two-photon laser for biomedical applications.
Investigated new radical photoinitiators based on aliphatic alpha-ketoester structures.
Tested physical and chemical integration of a stabilizing gelatin matrix for improved stability.
Developed disulfide-based hydrogels that showed effective photoreaction under two-photon irradiation.
Identified aliphatic photoinitiators as highly reactive and safer alternatives to conventional aromatic ones.
These systems exhibited excellent compatibility with various monomers for lithographic applications.

Explores biocompatible polymer systems using light to enhance degradation and safety.

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Antonella Fantoni (2026) studied this question.

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