This research aims to explore how O-GlcNAcylation relates to T-cell activation in allergic rhinitis during different pollen seasons.
Analyzed levels of O-GlcNAcylation in T-cells from patients with allergic rhinitis.
Monitored changes across natural pollen seasons.
Correlated findings with allergen exposure periods.
O-GlcNAcylation levels in T-cells increased post-pollen season.
Seasonal patterns reflect periods of immune activation.
Potential for using O-GlcNAcylation as a biomarker for immune responses.
Abstract
Summary O‐GlcNAcylation is a potential biomarker of off‐season immune activation in allergic rhinitis. Seasonal changes in O‐GlcNAcylation mirror allergen‐driven T‐cell activation.