T Cell O‐ GlcNAcylation Increases in Patients With Allergic Rhinitis After the Natural Pollen Season

Eduardo I. Cardenas; Maryam Jafari; Emma Nilsson; Agnetha Karlsson; Marianne Petro; Monika Ezerskyte; Ola Winqvist; Lars‐Olaf Cardell

doi:10.1111/cea.70311

April 20, 2026Clinical & Experimental AllergyOpen Access

T Cell O‐ GlcNAcylation Increases in Patients With Allergic Rhinitis After the Natural Pollen Season

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Key Points

This research aims to explore how O-GlcNAcylation relates to T-cell activation in allergic rhinitis during different pollen seasons.
Analyzed levels of O-GlcNAcylation in T-cells from patients with allergic rhinitis.
Monitored changes across natural pollen seasons.
Correlated findings with allergen exposure periods.
O-GlcNAcylation levels in T-cells increased post-pollen season.
Seasonal patterns reflect periods of immune activation.
Potential for using O-GlcNAcylation as a biomarker for immune responses.

Implication

Investigating O-GlcNAcylation effects on immune activation in allergic rhinitis, suggesting seasonal influences.

Abstract

Summary O‐GlcNAcylation is a potential biomarker of off‐season immune activation in allergic rhinitis. Seasonal changes in O‐GlcNAcylation mirror allergen‐driven T‐cell activation.

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Cite This Study

Cardenas et al. (2026) studied this question.

synapsesocial.com/papers/69e8677e6e0dea528ddeb9b7 https://doi.org/10.1111/cea.70311

View Full Paper

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T Cell O‐ GlcNAcylation Increases in Patients With Allergic Rhinitis After the Natural Pollen Season

Key Points

Implication

Abstract

Discussion

Cite This Study

T Cell O‐ GlcNAcylation Increases in Patients With Allergic Rhinitis After the Natural Pollen Season

Key Points

Implication

Abstract

Discussion

Cite This Study

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