Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk

Alice W. Lee; Roberta B. Ness; Lynda D. Roman; Kathryn L. Terry; Joellen M. Schildkraut; Jenny Chang-Claude; Jennifer A. Doherty; Usha Menon; Daniel W. Cramer; Simon A. Gayther; Harvey Risch; Aleksandra Gentry-Maharaj; Marc T. Goodman; Francesmary Modugno; Ursula Eilber; Kirsten B. Moysich; Andrew Berchuck; Mary Anne Rossing; Allan Jensen; Kristine G. Wicklund; Kara L. Cushing-Haugen; Estrid Høgdall; Anja Rudolph; Pamela J. Thompson; Lynne R. Wilkens; Susanne K. Kjær; Michael E. Carney; Daniel O. Stram; Susan J. Ramus; Anna H. Wu; Malcolm C. Pike; Celeste Leigh Pearce

doi:10.1097/aog.0000000000001387

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Abstract

We found evidence of an increased risk of serous and endometrioid ovarian carcinoma associated with postmenopausal estrogen-only therapy use, particularly of long duration. These findings emphasize that risk may be associated with extended estrogen-only therapy use.

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Lee et al. (2016) studied this question.

synapsesocial.com/papers/69e93cd62ebb62c3ea8b7031 https://doi.org/10.1097/aog.0000000000001387

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Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk

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Association Between Menopausal Estrogen-Only Therapy and Ovarian Carcinoma Risk

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