Cross-sectional analysis shows that key insulin resistance metrics influence anemia prevalence in older adults, suggesting metabolic links.
Higher levels of TyG, TG/HDL-C, and METS-IR are associated with lower prevalence of anemia, whereas higher eGDR is associated with higher anemia prevalence in middle-aged and elderly Chinese adults. These findings highlight complex metabolic-hematologic interactions, though the cross-sectional design precludes causal inference. Further longitudinal research is warranted to elucidate the underlying mechanisms.
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Chen et al. (2026) studied this question.
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