Behavioral variant frontotemporal dementia initially diagnosed by long-standing walking habit: an autopsy case

January 1, 2026Rinsho ShinkeigakuOpen Access

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Key Points

The aim is to illustrate a case where long-standing walking habits led to the diagnosis of behavioral variant frontotemporal dementia associated with corticobasal degeneration.
Case report of a 78-year-old male with a history of long-distance walking due to diabetes.
Clinical diagnosis of behavioral variant frontotemporal dementia followed by post-mortem examination confirming corticobasal degeneration.
The subject exhibited compulsive walking behavior characterized by an inability to control the urge.
Pathological examination identified corticobasal degeneration affecting frontal and temporal lobes, possibly linked to the impulse-control behavior.

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An autopsy case reveals behavioral variant frontotemporal dementia diagnosis from walking habits, suggesting deeper neurological issues.

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Kikuchi et al. (2026) studied this question.

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