Staphylococcus aureus is a prevalent pathogen that poses significant threats to human health due to its virulence and biofilm formation. It persists outside the host and induces a wide range of infections owing to its adaptability and resistance to environmental stresses in diverse host niches. The complex architecture of their regulatory network influences their potential to survive in these stressful circumstances. This article comprehensively discusses the multifaceted stress-adaptive responses in host-specific niches to develop therapeutic strategies for combating this highly contagious pathogen. Understanding the survival tactics of S. aureus offers insights into potential treatments that can mitigate its impact in biomedical applications.
Selvam et al. (Tue,) studied this question.