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April 23, 2026BMC GeriatricsOpen Access

The association between sarcopenia and frailty in older adults: a moderated mediation model

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Authors

SGShasha GaoHZHailong Zhang

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Overview

Investigates the relationship between sarcopenia and frailty in older adults, suggesting functional limitations and grip strength play important roles.

Key Points

  • This research aims to explore how functional limitations mediate the relationship between sarcopenia and frailty, with grip strength moderating this effect.
  • Analyzed data from 2,885 individuals aged 45 and above from the China Health and Retirement Longitudinal Study.
  • Utilized Spearman correlation analysis and PROCESS version 3.5 to test mediation and moderation effects.
  • Sarcopenia was prevalent in 15.9% of the elderly population studied.
  • Functional limitations mediated 26.23% of the effect of sarcopenia on frailty.
  • Handgrip strength negatively correlated with sarcopenia, frailty, and functional limitations.

Cite This Study

Gao et al. (2026) studied this question.

synapsesocial.com/papers/69e9b91385696592c86ebf2bhttps://doi.org/10.1186/s12877-026-07529-0
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