Demonstrates a nickel-catalyzed method to create functionalized alkenes from vinylarenes using vinylsiloxanes, indicating a versatile application in chemistry.
We report the first directing-group-free nickel-catalyzed difunctionalization of vinylarenes using bench-stable vinylsiloxanes as alkenylating agents. This mild, scalable and stereospecific method provides regioselective access to functionalized disubstituted alkenes with broad scope, low catalyst loadings, and minimal Z-isomerization, establishing vinylsiloxanes as versatile alkenyl transfer partners in multicomponent nickel catalysis.
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Salamone et al. (2026) studied this question.
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