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Demonstrates a new method to synthesize spirooxindole-lactones in water, indicating an efficient chemical process.
We present a I₂-mediated oxidative dearomatization of carboxylic acid-tethered indole derivatives, enabling the synthesis of diverse spirooxindole-lactones in water. Isotope labelling studies demonstrated a dual role for water, acting as...
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Liu et al. (2026) studied this question.
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