Demonstrates the relationship of CD105 with disease aggressiveness in oral squamous cell carcinoma, suggesting its role in patient prognosis.
An elevated MVD by CD105 expression is strongly correlated with aggressive HSPL features, stage, nodal metastasis, and poor prognosis in OSCC. In addition to prognostic information, CD105 has the potential to be a target for anti-angiogenic strategies in OSCC indicating its potential use in clinical risk stratification and planning.
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Gadbail et al. (2026) studied this question.
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