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January 28, 2017SHILAP Revista de lepidopterologíaOpen Access

Astrocyte IKKβ/NF-κB signaling is required for diet-induced obesity and hypothalamic inflammation

John D. Douglass Mauricio D. Dorfman Rachael Fasnacht L.D. Shaffer Joshua P. Thaler

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Abstract

These data support a requirement for astrocytic inflammatory signaling in HFD-induced hyperphagia and DIO susceptibility that may provide a novel target for obesity therapeutics.

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Douglass et al. (2017) studied this question.

synapsesocial.com/papers/69eaad0a7ebffcff75ccf6d5 https://doi.org/10.1016/j.molmet.2017.01.010

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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