Severe numbness of the mouth and tongue induced by piperacillin/tazobactam: a rare case report

Xinqi Huang; Wanlin Liu; Bo Tan; 実 立川; Yongliang Huang; Shuting Wang; Nianqing Yin; Yi Li; Liutao Zheng; Yanli Dai

doi:10.1080/20565623.2026.2653792

April 21, 2026Future Science OAOpen Access

Severe numbness of the mouth and tongue induced by piperacillin/tazobactam: a rare case report

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Key Points

To highlight a rare adverse reaction of severe numbness of the mouth and tongue associated with piperacillin/tazobactam.
Case report detailing symptoms and clinical management
Monitoring of adverse drug reactions during treatment
Patient experienced severe numbness after administration of piperacillin/tazobactam.
Negative skin tests did not predict the adverse reaction.

Implication

Case report reveals severe numbness from piperacillin/tazobactam, suggesting vigilance is necessary.

Abstract

This case suggests that during clinical use of piperacillin/tazobactam, clinicians should remain vigilant for rare but severe adverse drug reactions even when skin testing is negative, and strengthen medication monitoring to ensure medication safety.

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Cite This Study

Huang et al. (2026) studied this question.

synapsesocial.com/papers/69eb084f553a5433e34b360b https://doi.org/10.1080/20565623.2026.2653792

View Full Paper

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Severe numbness of the mouth and tongue induced by piperacillin/tazobactam: a rare case report

Key Points

Implication

Abstract

Discussion

Cite This Study

Severe numbness of the mouth and tongue induced by piperacillin/tazobactam: a rare case report

Key Points

Implication

Abstract

Discussion

Cite This Study

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