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This research evaluates kidney function indicators in young adults born prematurely compared to those born at term.

April 24, 2026Pediatric Nephrology2 citationsOpen Access

Young adults born moderately to extremely preterm have higher eGFR and cystatin C compared to young adults born at term

TSTyler T. ShimfesselSouthwestern Medical Center GBGregory P. BartonVascular / Pulmonary Vascular KDKeri A. DrakeSouthwestern Medical Center

Key Points

This research evaluates kidney function indicators in young adults born prematurely compared to those born at term.
Compared eGFR and cystatin C levels among individuals born moderately to extremely preterm and those born at term.
Analyzed creatinine levels to assess kidney function.
Conducted a comparative study of kidney function between two groups.
Individuals born prematurely exhibited higher eGFR than those born at term.
Cystatin C levels were also elevated in the preterm group.
These findings suggest a possible risk for chronic kidney disease progression in individuals born preterm.

Abstract

Despite similar creatinine, individuals born prematurely had higher eGFR and higher cystatin C. The elevated eGFR suggests a potential hyperfiltrative state, while the elevated cystatin C suggests increased risk for progression to chronic kidney disease.

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