Echocardiography reliably assessed right ventricular function in COPD patients, demonstrating a significant correlation between 2D RV end-diastolic diameter and radionuclide RV EF (r=0.60, p<0.005).
Observational (n=26)
Are echocardiography and radionuclide ventriculography reliable methods for assessing right ventricular function in COPD patients with and without pulmonary hypertension?
Echocardiography and radionuclide ventriculography provide reliable assessments of right ventricular function that correlate well with mean pulmonary artery pressure in COPD patients.
Estimación del efecto: r = 0.60
valor p: p=< 0.005
Twenty-six patients with chronic obstructive pulmonary disease (COPD) underwent echocardiography and radionuclide (RN) ventriculography on the same day. Patients were divided into two groups: group 1 consisted of 11 patients without pulmonary hypertension with a mean pulmonary artery pressure (mPAP) of 13.91 ± 4.21 mm Hg, and group 2 consisted of 15 patients with pulmonary hypertension (mPAP: 31.40 ± 6.96 mm Hg). The 2D-echocardiographic results showed that the right ventricle (RV) diameter was larger than normal in both groups of patients, especially in group 1. The RV inflow diameter was high in group 2, while in group 1 it was in the normal range. The parameters studied during RN vetriculography were the global RV ejection fraction (EF), the RV inflow EF and outflow EF. RV global EF was lower than normal in both groups of patients. Outflow EF was normal in group 1, but was lower in group 2. RV inflow EF was low in both groups. The simple correlation between the 2D RV end-diastolic diameter and RN RV EF was r = 0.60 (p < 0.005). The simple correlation coefficient between RV inflow EF and RV inflow diameter was r = 0.60 (p < 0.001), although the correlation coefficient between RV outflow diameter and RV outflow EF was low. The multiple correlation between RV diameters and mPAP was 0.72 (p < 0.0001) and the multiple correlation between RV EF and mPAP was 0.65 (p < 0.005). In conclusion, echocardiography was found to be a reliable method of assessing RV function in COPD patients, especially those with pulmonary hypertension.
Marangoni et al. (Fri,) conducted a observational in Chronic obstructive pulmonary disease (COPD) (n=26). Echocardiography and radionuclide ventriculography vs. Patients without pulmonary hypertension vs patients with pulmonary hypertension was evaluated on Correlation between 2D RV end-diastolic diameter and RN RV EF (r = 0.60, p=< 0.005). Echocardiography reliably assessed right ventricular function in COPD patients, demonstrating a significant correlation between 2D RV end-diastolic diameter and radionuclide RV EF (r=0.60, p<0.005).