Diastereoselective Synthesis of β-Hydroxy Allylic Tertiary Sulfides via Nickel/Photoredox Cooperative Catalysis

Key Points

• The study aims to develop an effective synthesis method for β-hydroxy allylic sulfides to overcome existing challenges.
• Utilized a nickel/photoredox cooperative catalysis system
• Focused on improving the diastereoselectivity
• Addressed issues related to sulfur-mediated catalyst poisoning
• Achieved successful diastereoselective synthesis of β-hydroxy allylic sulfides
• Demonstrated overcoming catalyst poisoning issues
• Indicated enhanced control over stereochemistry in the synthesized products