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April 22, 2026Diabetes Obesity and Metabolism

Bifidobacteriuradm bifidum G9‐1 Intake Improves Gastrointestinal Symptoms in Type 2 Diabetes Mellitus: An Open‐Label, Randomized Controlled Trial (Binary STAR Study)

Genki Kobayashi Yoshitaka Hashimoto Tomoyuki Matsuyama Noriyuki Kitagawa Saori Majima Takafumi Senmaru Emi Ushigome Hiroshi Okada Naoko Nakanishi Masahide Hamaguchi Michiaki Fukui

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Key Points

The aim is to examine the effects of Bifidobacterium bifidum G9-1 on gastrointestinal symptoms in type 2 diabetes.
Conducted an open-label, randomized controlled trial.
Assessed gastrointestinal symptoms in participants with type 2 diabetes.
Compared effects before and after Bifidobacterium bifidum G9-1 intake.
Participants reported significant improvements in gastrointestinal symptoms.
Findings suggest a beneficial effect of Bifidobacterium intake on symptom relief.
Results indicate promise for utilizing probiotics in managing gastrointestinal issues.

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Implication

Open-label trial shows improved gastrointestinal symptoms in type 2 diabetes, indicating potential benefits for management.

Abstract

Japan Registry of Clinical Trials (jRCTs051220127).

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Cite This Study

Kobayashi et al. (2026) studied this question.

synapsesocial.com/papers/69eb099a553a5433e34b3f7a https://doi.org/10.1111/dom.70805

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